|May 20, 2009
Some approaches mask or alleviate pain and inflammation by blocking certain enzyme activities in the body that may lead to discomfort. And in some cases, harmful effects—liver or kidney damage, stomach ulcers or bleeding, stroke, heart attack, further joint damage, and osteoporosis—have been reported with extended use. Get relief that works with your body for a higher degree of safety. Now you can get comfortable relief for pain without potential serious adverse effects. Laboratory tests‡ show that a THIAA combination (hops derivatives and other natural ingredients) effectively addresses the root causes of inflammation without the potential risks of directly blocking certain important enzyme activities. The Benefits of a THIAA Combination
Stress Induced Dysfunction: Here is a summary article on the nutritional management of stress induced dysfunction.
In today’s fast-paced society, the vast majority of individuals are under a constant barrage of stressors. Surveys and research reports conducted over the past two decades reveal that 43% of all adults suffer adverse effects due to stress. In fact, 75% to 90% of all visits to primary care physicians are in some way related to the adverse impacts that stress has on the body.1THE HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS Stressors trigger the HPA axis. The HPA axis then translates these stressors into signals that alter the body’s biochemistry to support a “fight or flight” response, also termed the stress response. The HPA axis is the primary regulator of this stress response. While stress-induced changes in biochemistry may be beneficial to survival in the short term (acute stress), they present an increased risk of various health challenges in the long term (chronic stress).2-4Dysfunction of the HPA axis brought on by repeated exposure to stressors may curtail life expectancy by several years due to its downstream effects on physiology and organ/system function.4,7Research increasingly supports the critical role that stress can play in obesity, diabetes, osteoporosis, hypertension, cardiovascular disease, infectious disease, gastric ulcer, cancer, and gastrointestinal, skin, psychological, and neurologic disorders, as well as a host of disorders linked to immune system disturbances.1,4,5,7-11COMBATING STRESS WITH HERBAL ADAPTOGENS Fortunately, lifestyle changes such as stress reduction, relaxation, regular exercise, and a healthy diet can all support a healthy response to stress. In addition, many herbs referred to as “adaptogens” have been used over the centuries in traditional medicine and have clear empirical and clinical evidence of their ability to support a healthy response to stress and normalize HPA activity.27 Adaptogens, by nature, have a variety of beneficialeffects, such as increasing energy and stamina, preventing fatigue, enhancing memory and concentration, and improving work performance.27,28 Such adaptogenic herbs include:Holy Basil (Ocimum sanctum)—Holy basil is an Indian herbwith a rich history of treating a variety of conditions. It has repeatedly shown to modulate stress response activity in animal testing. For instance, treatment with holy basil decreased the incidence of gastric ulcer, increased physical endurance, and lowered the stress-induced release of adrenal hormones and cholesterol in animal studies.27,29-35Ashwagandha (Withania somnifera)—Known as a classic rejuvenatingherb in Indian medicine, ashwagandha has been shown to enhance adaptability to both physical and chemical stress. For instance, mice pretreated with ashwagandha and subjected to physical stress showed increased endurance. Additionally, ashwagandha has been shown to prevent ulcers and other symptoms associated with the stress response.27,36-38Bacopa (Bacopa monnieri)—Bacopa is traditionally used torevitalize nerves and the mind, as well as to help strengthen the adrenals. In animal testing, bacopa has been shown to improve adaptations in sensory, motor, and motivational systems.43-48Cordyceps (Cordyceps sinensis)—Cordyceps is a therapeuticfungus found primarily at high altitudes in China and is one of the most valued medicinal fungi in Chinese medicine. Research dating back to 1843 suggests the use of cordyceps to help strengthen and rebuild the body after exhaustion or long-term illness.49-53Asian Ginseng (Panax ginseng)—Ginseng is greatly valued as atonic—a substance that acts to normalize body function and biochemistry. According to traditional Chinese medicine, the individual who will benefit from ginseng is overwhelmed and exhausted.54-59Rhodiola (Rhodiola rosea)—Rhodiola is widely distributed athigh altitudes in the Arctic and mountainous regions throughout Eastern Europe and Asia, where it is traditionally used to stimulate the nervous system, decrease depression, enhance work performance, and eliminate fatigue.64-66Licorice (Glycyrrhiza glabra)—Of the many herbs available,licorice is one of the most highly regarded in terms of treating conditions associated with diminished adrenal function.55-70THE HPA/THYROID LINK Stress-induced HPA dysfunction may also hinder the proper function of the metabolic regulator, the thyroid. Research suggests that high levels of stress affect the synthesis of thyroid hormones (T4, T3) and negatively impacts their metabolism.19,20 Theend result is reduced thyroid hormone activity and the accompanying health challenges, which include weight gain, lethargy, reproductive failure, depression, irritability, memory loss, muscle weakness, and more serious long-term effects, such as congestive heart failure.23NUTRITIONAL SUPPORT FOR HEALTHY THYROID HORMONE ACTIVITY Specific combinations of nutrients may support 1.) thyroid hormone synthesis, 2.) the conversion of T4 to the more bioactive T3, and 3.) the expression of thyroid hormone responsive genes. Taken together these activities may promote the optimal health of individuals with thyroid hormone issues originating from insufficient metabolism or activity of thyroid hormone. These nutrients include: Bladderwrack—Bladderwrack is an algae that provides a naturalsource of iodine, which is required for the synthesis of T4 in the thyroid gland.77,78Selenium—Due to its role as a cofactor for the enzyme 5’-deiodinase,which converts T4 to T3, selenium is essential for normal thyroid hormone metabolism and biological activity.19,20,81Zinc—Research suggests that zinc may play many roles in thyroidhormone homeostasis, including supporting T4 synthesis, 5’-deiodinase function, and healthy expression of thyroid hormone responsive genes.19,20,84Vitamin E—Vitamin E may support the conversion of T4 to T3by influencing hepatic 5’-deiodinase activity; it may accomplish this by protecting the stability of cell membranes in which 5’-deiodinase exists.86-88Vitamins A, D, and Carnosic Acid—These nutrients may providesupport for the binding of thyroid hormone receptors to DNA, thereby contributing to the healthy expression of thyroid hormone responsive genes.22,89-94While stress is an inevitable consequence of modern life, the downstream damage caused by chronic stress is not. A healthy diet, regular exercise, and relaxation are important factors in managing stress. In addition, adaptogenic herbs that help normalize parameters of the stress response and nutrients that support optimal thyroid hormone activity play an important role in supporting overall health and well-being throughout life.
In fact, clinical studies and safety research suggest this formula works without upset to many of the body systems that make other pain relievers potentially harmful. Don’t risk your health. Get natural relief from joint pain without potential serious adverse effects to your heart, liver, or stomach. If you’d like to know more, please contact my office to set up an appointment. We’ll work with you to design a program that will help you promote long-term joint health.
- A safer, clinically effective option to relieve joint pain
- Scientifically tested and shown to significantly affect inflammatory pathways—without reported serious adverse effects
- Clinical testing suggests a high degree of cardiovascular, gastrointestinal, kidney, and liver safety